Christine, 47, has dropped more than 100 pounds and now wears a size 10 medium

In 2010 Christine Biswabic weighed 278 pounds and wore a size 4X. She suffered daily with PCOS, high blood pressure and headaches. During a cold, snowy December Minnesota morning she was hit head on by 5 cars, including a large pickup truck and broke her neck.

Lying in the hospital bed for over 3 weeks she decided something had to change. In all, Christine, 47, has dropped more than 100 pounds and now wears a size 10 medium.

“Today,” she says, “I live SANE! I know what it’s like to feel free, with ease of mobility and an uncluttered mind... and that’s priceless.”

Within 3 months she had lost 45 pounds, and after 5 years of trying, she finally got pregnant

Cristina Hanganu-Bresch was diagnosed with diabetes, placed on cholesterol medicine and finally faced the reality that she would never have children after many years of trying with her husband Mark. The news came after a depressing meeting with a fertility specialist who gave her little hope for the future if her “numbers stayed where they were.”

She discovered SANE through a friend and embraced the small but powerful changes. Within 3 months she had lost 45 pounds, her cholesterol dropped from 220 to 103, she was taken off her diabetes meds and as she told me over email…

“There’s just one more thing: After 5 years of trying, I finally got pregnant!" Cristina sent me Mirunas picture a few months later, her name means 'peace'.

Even Christine's husband has embraced the changes and has lost 32 pounds, fixed his sleep apnea and stopped debilitating migraines. "Going SANE" isn’t about “you must do this” and “you can never do that.” She told me. “It is about using simple science instead of complex myths to live better—whatever your lifestyle.”

Dr. Cathy Britell ended decades of yo-yo dieting and lost 40 pounds while going from size 22 to a size 14

Dr. Cathy Britell specializes in rehabilitation medicine, but also had a second career as a “professional dieter and exerciser” as she put it. After 30 years she watched her weight go up, then down… then UP again, all the way to clinically obese at 225 pounds. She reached her low-point when she had an embarrassing episode on a flight coming home after the holidays with family in 2013.

Then Dr. Britell discovered the SANE way of eating more and exercising less but smarter. Right away, the pounds started to disappear. She reached the goal that had eluded her for decades, dropping 40 pounds and going from a size 22 to a size 14.

Looking better is only part of the story. Cathy had pre-diabetes, but now her blood sugars are normalized, and so are her lipids. “Now that I’ve lost the weight, everything seems like so much more fun.”