Vitamins and Other Nutrients that Help Lower Setpoint Weight

If you take vitamins just to increase levels of nutrients in your body, you’re missing out on a major benefit. Namely, nutraceuticals can help lower your setpoint weight. Nutraceuticals are natural compounds found in foods that have been concentrated down to pharmaceutical-grade levels. These include vitamins, minerals, amino acids, and essential fatty acids.An image of a word collage of words associated with vitamins, such as dosage, multi, and food.

Studies show these compounds can increase fat burning and lower setpoint weight when taken in conjunction with a higher-quality eating and exercise program. They are not diet pills, and they contain no stimulants or trigger any side effects. But they are an effective tool to help you lower your setpoint weight faster, melt away pounds, and look and feel great.

Importance of vitamins and other nutrients in weight loss

Trying to lose weight permanently can be frustrating. If weight loss is a constant struggle for you, you’re not alone. Statistics indicate diets fail more than 95% of the time. The reason for this failure rate is complex and will be explained shortly. But certain vitamins and other nutraceuticals can ignite your body’s natural fat-burning ability.

There is one caution, however. These vitamins and nutraceuticals will not work by themselves to lower your setpoint weight and help you trim down. They will work only if you incorporate them into a SANE eating plan and lifestyle. Once you do that, you will be amazed at the rapid results you will see by taking these vitamins and other nutraceuticals.

What can you expect when you go SANE with vitamin and other nutrient regimens? For starters, yo-yo dieting will be a thing of the past. You will lose weight easily, without effort. But before this can happen, you’ll need to lower your setpoint weight.

3 factors that determine setpoint weight

There are 3 factors that determine setpoint weight: hormones, brain, and gut bacteria. If any of these three are out-of-whack, a hormonal clog occurs that elevates your setpoint weight. Let’s take them one at a time.

1. Hormones

Your hormones, your fat cells, and your gut are in constant communication. They monitor your fat stores, how many calories you’ve eaten, and everything else. Their mission is to keep you alive.

What hormones affect weight?

Hormones such as leptin, ghrelin, insulin, and cortisol affect our appetite, metabolism, and the distribution of body fat. Overweight individuals have imbalances in one or more of these hormones that contribute to body fat accumulation.


Leptin is a hormone released by adipose tissue (body fat) that helps maintain normal body weight over time. This is accomplished by providing a feeling of satiety (fullness) in order to regulate hunger.

How does this work? Your fat cells make leptin and secrete it into the bloodstream. Leptin goes to your brain and tells it how much energy you have, via your fat stores, to support your metabolic processes. When you go on a starvation diet, you lose some fat, and your fat cells produce less leptin. The leptin level in your blood goes below what is normal for you. Your brain senses starvation.

This triggers several metabolic processes to get your leptin levels back up to normal. The first is that the vagus nerve is stimulated. (The vagus nerve runs between your stomach and your brain.) This makes you hungry.


Ghrelin is produced and released primarily by the stomach, although small amounts are also released by the brain, pancreas, and intestine. It circulates in the bloodstream and goes to the hypothalamus, an area of the brain in charge of appetite control. Known as the “hunger hormone,” ghrelin stimulates appetite and encourages fat storage.

Ghrelin is regulated primarily by food intake. Research shows ghrelin may cause the hunger pangs you experience right before meal times. Your diet also determines the levels of ghrelin in your blood. For instance, research shows that protein restricts the production and release of ghrelin. That’s one of the reasons protein is so filling.

And here’s another interesting thing about ghrelin: levels of this hormone increase after dieting. This partially explains why it’s so easy to regain weight after dieting. You’re more hungry after your diet than you were before it even began!


Insulin is a hormone produced by the pancreas that helps move glucose into your cells for energy after it reaches your bloodstream. But insulin is also a fat-storage hormone that tells your body to stop burning fat and to store more fat.

When you routinely eat inSANE foods, such as starchy carbs and sugars, insulin is almost always circulating in your bloodstream. This keeps you in fat-storage mode rather than fat-burning mode. A SANE diet, vitamins, and nutraceutical plan will take care of this.


Cortisol, the principal stress hormone, increases blood sugar (glucose), promotes the brain’s usage of glucose, and increases the availability of chemicals that aid in tissue repair.

It also contributes to weight gain and fat distribution. For example, stress causes cortisol levels to rise, triggering higher levels of insulin. Because insulin helps clear excess glucose from the bloodstream, a high level of this hormone can cause a sudden drop in your blood sugar levels, which can lead to cravings for sugary, fatty foods.

Studies also show that elevated cortisol levels promote fat storage, especially in the abdominal area, which can contribute to many serious health conditions.

2. Brain

The second factor that determines your setpoint weight is the brain. The hypothalamus in your brain controls and regulates your metabolism. All the metabolic hormones give constant status reports to the hypothalamus so that it can order appropriate action. If the hypothalamus becomes inflamed, it cannot receive these signals. Your setpoint weight then goes up.

Researchers have discovered that an inflamed hypothalamus is one of the causes of overweight and obesity. Indeed, in one study, the brains of humans and rodents began to show signs of inflammation in just 24 hours after eating an inSANE diet. If they continued eating inSANEly, the hypothalamus became severely inflamed and showed structural damage.

This, too, can be addressed with a SANE diet, vitamins, and nutraceutical therapy.

3. Gut

The final factor that determines setpoint weight is the gut. Gut bacteria are extremely important for your weight. They extract calories from the food you eat and store them for later use. An imbalance of good and bad gut bacteria affects your health and your weight. Indeed, research has found resetting the balance of intestinal microbiota in favor of those bacteria known to promote weight loss causes significant weight loss.

Studies show that these tiny organisms even influence the foods you crave. For instance, one type thrives better on fiber, and one type likes carbs, etc. This knowledge gives you an added tool to lower your setpoint weight. After all, once you start eating SANE foods, you will feed the lower setpoint bacteria and starve the higher setpoint bacteria.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your FREE Weight Loss Recipes, the “Eat More, Lose More” Weight Loss Recipes, the “Slim in 6” Cheat Sheet…CLICK HERE TO GET FREE WEIGHT LOSS RECIPES & GUIDES

How do these 3 factors affect the setpoint weight?

Your brain, gut, and hormones talk to one another to synchronize the activities that automatically maintain body fat at a specified level. This is your setpoint weight. Your body defends this weight at all costs. As previously mentioned, if you go on a crash diet, your hormones send signals to the brain that makes it think you’re starving.

The hypothalamus signals ghrelin to make you hungry. You’ll become cold and crave your favorite foods. If that isn’t enough to make you eat to restore your leptin levels, it slows your metabolism.

This is why a typical diet doesn’t work. Sure, everybody loses weight on most diets in the beginning. But then it slows down to almost nothing. Your body is fighting you every step of the way. When you finally go off the diet because you’re so frustrated at your lack of progress, you’ll probably eat more food than you did before the diet. This is because dieting itself increased your levels of the hunger hormone ghrelin. Overeating combined with a slower metabolism ensures you’ll gain back all the weight you lost. You’ll even gain an additional few pounds as added insurance against future starvation.

It should be clear by now that the calorie-deficit theory of weight loss is wrong. The calorie-deficit theory of weight loss treats the metabolism like a scale, calories in = calories out. But the metabolism is not like a scale, it is like a thermostat. It regulates calorie input and output around your setpoint weight. This system ensures you’ll never be too heavy or too thin unless the system is damaged or broken. When the system is damaged, you will have an elevated setpoint weight.

Causes of an elevated setpoint weight

There are several causes of an elevated setpoint weight. Here are the most common causes:

  • Poor-quality diet: Research shows that routinely eating an inSANE diet of processed foods, sugars, and starchy carbs raises setpoint weight.
  • Environmental toxins: From herbicides on plants to air pollution from car exhausts, we are surrounded by environmental toxins. Continual exposure to toxins elevates setpoint weight, causing weight gain.
  • Sleep deprivation:  Research shows sleep deprivation contributes to weight gain. One of the reasons is that it increases levels of cortisol. This causes fat accumulation in the stomach. Cortisol also increases cravings for starchy carbs.
  • Chronic stress:  This also elevates setpoint weight, and the culprit is, again, cortisol. When you’re stressed, your adrenal glands release cortisol. If the stress goes on too long, it contributes to a higher setpoint weight.

If you have an elevated setpoint weight, it is likely due to a combination of the factors above. The good news is that a SANE lifestyle, when combined with vitamins and other nutrients, can reverse hormonal dysregulation, brain inflammation, and gut dysbiosis, thereby lowering setpoint weight.

Vitamin and other nutrients that help lower setpoint weight

Here are the vitamins and other nutriceuticals that research proves can lower setpoint weight when used in conjunction with a SANE lifestyle.

Vitamins and other nutraceuticals for fat burning

Here are some excellent vitamins and other nutraceuticals for fat burning.

  • Inositol: This nutrient assists in fat transportation and metabolization. It also normalizes blood sugar levels and reduces hunger. Recommended daily dosage: 1,000 mg with food.
  • Choline: This essential B vitamin works with inositol to help the body properly use fat. Recommended daily dosage: 1,000 mg with food.
  • Betaine HCI: A derivative of choline, studies show Betaine HCL may reduce body fat. It also helps heal gut inflammation, one of the factors in an elevated setpoint weight. Recommended dosage: 100 mg.
  • Vitamin B-12: This essential vitamin plays a role in converting fat to energy. It also helps prevent brain inflammation, which can keep you from having an elevated setpoint weight. Recommended dosage: 100 micrograms.
  • Biotin: This B vitamin helps the body convert food into energy. It also regulates blood sugar, insulin, and the metabolism of fats and protein. Recommended dosage: 450 micrograms.
  • Methionine: This amino acid speeds fat from the liver to be released and used as energy. Recommended dosage: 1,000 mg.
  • L- Carnitine: This amino acid sends body fat into the energy-producing part of your cells, the mitochondria, allowing for more efficient fat burning. Recommended dosage: 600-1200 mg.
  • Chromium Picolinate: Chromium picolinate has been shown to reduce insulin resistance, fight food cravings, and burn fat. Recommended dosage: 200 micrograms.
  • Coenzyme Q10 (CoQ10): The body makes this natural antioxidant. However, many people have insufficient levels of CoQ10, especially as they age. This necessary nutrient converts fat and sugar to energy in cells. It also increases fat burning and fights chronic inflammation. Recommended dosage: 10 mg.
  • L-Leucine: This essential amino acid is the most powerful one for stimulating muscle-protein synthesis, which helps you build muscle and burn fat. Recommended dosage: 2 grams per meal.

Vitamins and other nutraceuticals that fight inflammation

  • EPA and DHA: These vital nutrients are found in seafood. When purchased at pharmaceutical-grade levels, they reverse inflammation. Recommended dosage: 1 tablespoon of cod liver oil per day.
  • Vitamin D3: This vitamin helps heal brain inflammation, which can lower setpoint weight. Vitamin D3 also provides many other health benefits. Recommended dosage: 5,000 IU
  • Prebiotics and Probiotics: These increase beneficial bacteria in your gastrointestinal tract, helping heal gut inflammation and lower your setpoint weight. Recommended dosage: as directed on the package or bottle.
  • L-Glutamine: This amino acid heals gut inflammation. Recommended dosage: 5 grams daily.

Vitamins, nutraceuticals, and the SANE Diet

The SANE diet, combined with these vitamins and nutraceuticals, will help lower your setpoint weight. There are 4 basic SANE food groups.

  • Non-starchy vegetables: Try to consume at least 10 servings per day, emphasizing green leafy vegetables. Some great non-starchy vegetable choices include spinach, kale, broccoli, onions, bell peppers, and cabbage.
  • Nutrient-dense proteins: 3-5 servings per day, approximately 30-50 grams of protein per meal. Some delicious nutrient-dense protein options include grass-fed beef, salmon, nonfat Greek yogurt, cottage cheese, chicken, and egg whites.
  • Whole-food fats: 3-5 servings per day. Some great whole-food fats for you to try include flax seeds, coconut, olives, almonds, and avocado.
  • Low-fructose fruit: 0-3 servings per day. Top off your meal with a yummy serving of low-fructose fruit. Some terrific choices include oranges, strawberries, goji berries, peaches, blueberries, and lemons.

Eating SANE Foods and taking these vitamins and other nutraceuticals will lower your setpoint weight easily and quickly.

Next step: Get the correct vitamins with SANE

Ready to finally break free from the yo-yo dieting rollercoaster by balancing your hormones and lowering your body’s setpoint weight?

Want to know the exact foods and serving sizes that are scientifically proven by over 1,300 peer-reviewed research studies to boost metabolism burn fat, and enjoy virtually effortless weight loss like a naturally thin person?

Download the free SANE metabolism boosting food list, cheat sheet, and “Eat More, Burn More” weight loss program by .

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your FREE Weight Loss Recipes, the “Eat More, Lose More” Weight Loss Recipes, the “Slim in 6” Cheat Sheet…CLICK HERE TO GET FREE WEIGHT LOSS RECIPES & GUIDES

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