Vitaae Reviews: Does This Brain-Health Supplement Really Work?

Does SANE Vitaae™ Really Work?

If you’ve been wondering if SANE Vitaae™ really works, you’ve come to the right place. We have received thousands of 5-star customer reviews attesting to the effectiveness of this brain-boosting natural supplement.

does sane work

Here is just one of many customer reviews of this amazing product:


SANE Vitaae™ is great stuff! I have been taking SANE Vitaae™for a year now, and I have seen improvements. My mind is sharper, my overall memory has improved, and I have significantly less brain fog!! I recently placed a large order because I definitely don’t want to run out of this great product. Happy Texas Customer!

-Monica S. (Verified Buyer)


What is SANE Vitaae™? 

Sane Vitaae™ is the world’s first ever clinically proven brain-boosting memory protecting formula. You won’t find this same blend of natural nutrients anywhere!

The natural ingredients in Vitaae™ work together synergistically to reduce or eliminate neurological inflammation, the hidden cause of brain fog, poor memory, low energy, weight gain, and mood disorders such as depression and anxiety.

It is clinically proven to enhance brain function, thereby improving many aspects of health.

Before we dig into the details of Vitaae™, let’s hear from another satisfied user.


“I was a nurse for 30 years. So I put a lot of attention to what I put into my body, and I am always hesitant about supplements. But I have to say after doing my own in-depth research on the formulation, the ingredients, especially the well studied patented versions, are really top notch.”

-Helen K

The Problem with Brain Inflammation

If you are struggling with low-energy, anxiety, depression, mood swings, brain fog, trouble focusing, a slowing metabolism, memory loss or any other brain related symptoms often accepted as “just part of life” or “just a part aging”, you’ll want to pay particular attention to this article.

You see, many of these symptoms may be caused by what doctors call neurological inflammation. Your brain is the control center of your body, so if it becomes inflamed, it can cause many varied symptoms not usually considered brain related.

And that’s a problem.

Fortunately, SANE Vitaae™ is the anti-aging solution for brain inflammation and its negative effects, as these customer reviews attest.

More Customer Reviews


“It’s safe to say that I have never tried anything, prescription medications included, that have had such an immediate and noticeable impact on my life everyday. Thanks!”

-Gloria R


“This can be a little sensitive, but I’m a middle school principal and now mention this to parents after seeing what it has done for me and my kids. It’s not an exaggeration to say that we’ve found it to be more effective than other options on many occasions and we’re extremely grateful.”

-Stacy S


Vitaee™ Helps Fix Leaky Brain Syndrome!

There are several dangerous infections and injuries that can cause acute brain inflammation, such as encephalitis. Fortunately, these conditions are rare.

Much more common is chronic brain inflammation due to leaky brain.

You see, inflammation is the body’s natural response to protect itself from toxins, pathogens, viruses or any other type of trauma or injury. Usually your brain is protected by the blood brain barrier.

But if this fragile blood-brain barrier is damaged, it becomes “leaky”. This allows toxins, pathogens and bacteria to enter the brain, activating what are called microglia cells that cause inflammation. Doctors call this “leaky brain syndrome.”

This inflammatory response can then shut down energy production in brain cells, causing your brain to literally slow down as your neurons are firing slower. This not only causes mental fatigue, but as you can imagine, shutting down energy production in brain cells and slowing down the firing of neurons severely breaks down every system in the body.

Fortunately, the natural ingredients in Vitaae™ can help fix leaky brain and reduce or eliminate neurological inflammation, which in turn provides numerous health benefits.

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Health benefits of SANE Vitaae™ Supplement


Here are just three of the scientifically backed health benefits of the ingredients in Vitaae™.

Supports Healthy Brain Function

It has become increasingly common for people to struggle with memory issues, brain fog, and trouble focusing and/or concentrating as they get older. But did you know poor cognitive performance is not necessarily a normal part of aging? Rather, these issues are likely caused by brain inflammation.

A study published in the Journal of Neuroscience stated:

“Stress-induced neuro-inflammation impairs hippocampal neurogenesis and promotes cognitive and affective behavioral deficits.”1


This is just a fancy way of saying that neurological inflammation can be the root cause of so many of the memory, focus and concentration issues we face as the years tick by.

An Inflamed Brain and Alzheimer’s Disease

But there’s more.

Neurological inflammation has long been associated with Alzheimer’s,2 a progressive brain disease that usually begins with mild memory loss and then becomes more severe and disabling over time.

According to the Alzheimer’s Association, more than 6 million Americans have this debilitating disease.3

Another study published 2014 found that:

“Compelling evidence from basic molecular biology has demonstrated the dual roles of the brains inflammation response in the pathogenesis of Alzheimer’s disease.”4


This research truly is cutting edge and only now making its way into mainstream medical thought that reducing brain inflammation could be THE key to slowing the progression of one of the scariest mental diseases of our time.

So if you suffer from brain fog, low energy, trouble focusing or other memory related problems, it’s not because you are getting older, it may be because you are suffering from severe neurological inflammation — which the Vitaae™ supplement may help resolve.

Relieves Anxiety and Depression

Anxiety and depression are two of the most common mental/mood disorders in the United States. Anxiety, for instance, affects an estimated 40 million adults in the U.S., or 18.1% of Americans, every year.5

And again, brain inflammation appears to play a role.

A 2017 Cambridge University study found that:

“Inflammation in the brain is increasingly being recognized as playing in a role in depression, and other mood disorders.”6

Another 2017 study published in Neurology Journal showed that participants that showed higher inflammatory brain activity had higher levels of depression and anxiety.7

By supporting brain health and decreasing neurological inflammation, this clinically proven nootropic supplement may help reduce the mental and emotional suffering of millions of people!

Boosts Metabolism and Enhances Weight Loss

Neurological inflammation can also dysregulate hormones, leading to slower metabolism and increased weight gain.

That’s right, weight gain and a slower metabolism as you age begins in your brain and specifically with inflammation of the hypothalamus.

The hypothalamus is the part of your brain that is in charge of balancing calories in and calories out so that ideally the body never becomes too fat or to thin.

But as almost everyone experiences as the years go by, this balance becomes upset and the body packs on extra pounds because it is getting the wrong messages from the brain and the hormones.

Inflammation of the hypothalamus and the imbalance in hormones increases what is called your setpoint weight… the 10 to 15 pound range that your hypothalamus and hormones work to keep your weight within.

The key is that new cutting-edge obesity research is finding that neurological inflammation leads directly to raising this setpoint weight and therefore slowing your metabolism and promoting weight gain.

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How Neurological Inflammation Promotes Weight Gain

How does this work?

The hypothalamus is located in the center of your brain and is regulated in large part by the hormones leptin and insulin. When the brain is healthy, these hormonal signals are received correctly so that when calorie intake increases your body simply burns more calories. In other words your weight balances at your setpoint weight. So, a healthy non-elevated setpoint means you automatically maintain a healthy weight… no dieting, calorie, point, or carb counting required.

However, neurological inflammation causes these signals to stop working and instead of trying to keep you naturally slim, your hypothalamus and hormones instead strive to hold on to extra fat, no matter how hard you try to lose the weight.

This means that neurological inflammation raises your setpoint and makes it is nearly impossible to lose extra weight until the inflammation is healed.

This connection between neurological inflammation and weight gain is breakthrough research that is changing the weight loss world forever. For example, a 2016 study in The Journal of Nutritional Biochemistry states:

“Current evidence shows hypothalamic inflammation as a likely mechanism for the dysregulation on the homeostatic control of energy balance, which leads to metabolic alterations and obesity.”8


Further, researchers at the University of Washington put simply:

“Obesity is associated with hypothalamic injury in humans.”9


And again, the Vitaae™ brain-boosting supplement can reduce neuroinflammation that in turn can help you reach and/or maintain a healthy weight.

More Vitaae™ Reviews

Here are a couple more Vitaae™ reviews from verified users.


You know how you go into a room and forget why? That doesn’t happen anymore. I had always been terrible with names, but it’s like they automatically stick in my mind now. I even remembered our wedding anniversary without any reminders this year (my wife couldn’t believe it).

-Robert W


At 62 Vitaae™  is the one thing that has really helped me to have a better attitude, a better outlook and a sharper mind. I feel like I have more energy and have lost 5 pounds already, as I am definitely more active. I have been so disappointed with the mental focus products out there because none have worked until trying Vitaae.

-Camilla A


What Are the Ingredients in  Vitaae™?

Here are the natural brain-health ingredients in SANE Vitaae™.

MagnaFolate C®

MagnaFolate C® is a patented form of folate that is more easily absorbed by the body.

You see, due to a genetic polymorphism impacting a lot of us, we can no longer produce the enzyme MTHFR and therefore cannot absorb the folate from ALL traditional sources (including even the healthiest, cleanest, most organic foods).

This means that that no matter what we eat or how many traditional supplements we take, many of us will suffer from chronically low levels of this critical brain nourishing nutrient.

And this is bad for your brain.

To show the importance of actually absorbing and optimizing your folate levels, take a look at these clinical studies:

King’s College Neurologists noted:

“It is becoming clear that folic acid affects mood and cognitive function, especially in older people.”10


And further:

“Within the wide spectrum of depressive disorders, a subgroup has been identified in which folate… [is] involved. With respect to dementia, there is evidence that folate deficiency may contribute to the cognitive impairment of the ageing brain… increasing the risk of Alzheimer’s disease and vascular dementia”.11

vitaae for throat phlegm


The studies on folate clearly show that to avoid age-related brain and memory problems, the need to get the proper amounts of folate cannot be overstated.


Cognazin™ is a patented form of citicoline, a brain-boosting ingredient that is just as critical as folate.

A study from the University of Oslo found that participants with lower blood levels of choline, the precursor to citicoline, had poor cognitive performance. The researchers also checked folate status and found that if both folate and choline were low , there was triple the risk for mental problems such as forgetfulness, trouble focusing, and brain fog.12

Citicoline is present in every cell in your body and especially vital to brain health.

You may have heard of the brain boosting power of it’s dietary precursor choline, which is the reason eggs are considered a good “brain food.”

Citicoline helps support your brain’s energy producing centers… which is critical because while your brain takes up just a tiny bit of your total body mass, at the very least it uses up 20 percent of your total energy.

This makes citicoline’s role in optimal brain function clear because citicoline supports the health of mitochondria13 which are the part of cells that produce energy in your brain.

In fact, the US Institute of medicine found that:

“Choline has a critical role in neurotransmitter function… and studies suggest that choline supplements increase dopamine receptor densities and can alleviate or improve memory impairment.”14

But here’s the key: To get optimal amounts of this nutrient, you would have to eat over a dozen eggs a day. That’s why the University of North Carolina found that a whopping 90% of the population are deficient.15

An Anti-Aging Powerhouse!

It’s so important for you to get optimal levels of citicoline because it has been clinically proven to help improve memory and learning,16 improve cognitive control,17 reduce memory impairments,18 and reduce the death of brain cells.19

The bottom line is that citicoline is another brain-boosting anti-aging powerhouse that 90% of us are deficient in and suffering silently as a result.

And Cognazin™, the patented form contained in the SANE Vitaae™supplement, is even better than regular citicoline.

In double blind randomized placebo controlled clinical trials, this new patented version of citicoline shows a 13.6% increase in brain energy utilization,20 and an almost 70% decrease in errors of omission, also known as “memory errors”.21

The SANE Vitaae™supplement can help you get the amount of citicoline your brain needs to function properly.

sane solutions vitaae reviews

Other Important Ingredients in SANE Vitaae™ Supplement

In addition, Vitaae™ contains several other natural ingredients to support brain health, reduce brain and bodily inflammation, boost metabolism, and help burn fat.

  • Vitamin D
  • Acetyl-l-carnitine
  • L-carnitine tartrate
  • Coenzyme Q10 (CoQ10)
  • Omega-3 fatty acids
  • Gymnema Sylvestre Leaf Extract


More Vitaae™ Reviews


I just love this! I have been taking it for 2 months now, and my brain fog is nearly gone. I have more energy. I exercise more, and I feel very vibrant all over, not just mentally. And I am down 7 pounds so that is a bonus.

-Terry L


This has literally changed the lives of everyone in my family. For me, I feel like those rare “moments of clarity” I used to have are just the way my mind works now. My husband says that he needs less time and coffee to “get going” in the morning and that things are just coming to him now.

-Katey W


After taking sane for three days I realized I finally had something that works! I no longer walk into a room and wonder why I’m there. I am 67 and I have never felt such mental clarity in a very long time. Much more energy much more peace!

-Peggy P


My mom has Alzheimer’s and did really well on Vitaae™ , getting a lot of her speech back. She decided to try 6 months without it and her speech declined quickly. She is taking it again now, and hoping her speech returns to the previous level.

-Jill S


vitaae reviews

Money Back Guarantee

A long with all the other great benefits, Vitaae™anti-aging formula comes with a 1-year (365 day) 100% money back guarantee.

We know you’ll love Vitaae™, but if for some reason you don’t, simply call or email our knowledgeable and friendly treatment experts for a full refund. No questions asked.

How great is that?

Side Effects of Taking Vitaae™

There are no known side effects of taking Vitaae™. However, we recommend that you speak with your doctor before taking this or other supplements. This is especially important if you are taking other supplements and/or prescription medications or have any health conditions.


1- McKim DB, Niraula A, Tarr AJ, Wohleb ES, Sheridan JF, Godbout JP. 

Journal of Neuroscience Mar 2, 2016. 36 (9) 2590-2604; DOI:

2- Latta CH, Brothers HM, Wilcock DM. Neuroinflammation in Alzheimer’s disease; A source of heterogeneity and target for personalized therapy. Neuroscience. 2015;302:103-111. doi:10.1016/j.neuroscience.2014.09.061

3- Alzheimer’s Association. Alzheimer’s Disease Facts and Figures. Accessed Jul 23, 2021.

4- Cai Z, Hussain MD, Yan LJ. Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer’s disease. Int J Neurosci. 2014 May;124(5):307-21. doi: 10.3109/00207454.2013.833510. Epub 2013 Sep 12. PMID: 23930978.

5- Anxiety & Depression Association of America. Facts & Statistics. Accessed Jul 23, 2021.,of%20disability%20worldwide.%20…%204%20Treatment%20Options.%20

6- Bevan-Jones WR, Surendranathan A, Passamonti L, et al. Neuroimaging of Inflammation in Memory and Related Other Disorders (NIMROD) study protocol: a deep phenotyping cohort study of the role of brain inflammation in dementia, depression and other neurological illnesses. BMJ Open. 2017;7(1):e013187. Published 2017 Jan 7. doi:10.1136/bmjopen-2016-013187

7- Rossi S, Studer V, Motta C, Polidoro S, Perugini J, Macchiarulo G, Giovannetti AM, Pareja-Gutierrez L, Calò A, Colonna I, Furlan R, Martino G, Centonze D. Neuroinflammation drives anxiety and depression in relapsing-remitting multiple sclerosis. Neurology. Sep 2017, 89 (13) 1338-1347; DOI: 10.1212/WNL.0000000000004411.

8- Cesar HC, Pisani LP. Fatty-acid-mediated hypothalamic inflammation and epigenetic programming. The Journal of Nutritional Biochemistry. Volume 42, 2017,Pages 1-6,

ISSN 0955-2863.

9- Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Obesity is associated with hypothalamic injury in rodents and humans. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. Erratum in: J Clin Invest. 2012 Feb 1;122(2):778. PMID: 22201683; PMCID: PMC3248304.

10- Reynolds EH. Folic acid, ageing, depression, and dementia. BMJ. 2002;324(7352):1512-1515. doi:10.1136/bmj.324.7352.1512

11- Reynolds EH. Folic acid, ageing, depression, and dementia. BMJ. 2002;324(7352):1512-1515. doi:10.1136/bmj.324.7352.1512

12- Nurk, E., Refsum, H., Bjelland, I., Drevon, C., Tell, G., Ueland, P., . . . Smith, D. (2013). Plasma free choline, betaine and cognitive performance: The Hordaland Health Study. British Journal of Nutrition, 109(3), 511-519. doi:10.1017/S0007114512001249

13- Nicolson GL. Mitochondrial Dysfunction and Chronic Disease: Treatment With Natural Supplements. Integr Med (Encinitas). 2014;13(4):35-43.

14- Institute of Medicine (US) Committee on Nutrition, Trauma, and the Brain; Erdman J, Oria M, Pillsbury L, editors. Nutrition and Traumatic Brain Injury: Improving Acute and Subacute Health Outcomes in Military Personnel. Washington (DC): National Academies Press (US); 2011. 9, Choline. Available from:

15- Zeisel SH, da Costa KA. Choline: an essential nutrient for public health. Nutr Rev. 2009 Nov;67(11):615-23. doi: 10.1111/j.1753-4887.2009.00246.x. PMID: 19906248; PMCID: PMC2782876.

 16- Petkov VD, Mosharrof AH, Kehayov R, Petkov VV, Konstantinova E, Getova D. Effect of CDP-choline on learning and memory processes in rodents. Methods Find Exp Clin Pharmacol. 1992 Oct;14(8):593-605. PMID: 1494300.

 17- Knott V, de la Salle S, Choueiry J, Impey D, Smith D, Smith M, Beaudry E, Saghir S, Ilivitsky V, Labelle A. Neurocognitive effects of acute choline supplementation in low, medium and high performer healthy volunteers. Pharmacol Biochem Behav. 2015 Apr;131:119-29. doi: 10.1016/j.pbb.2015.02.004. Epub 2015 Feb 12. PMID: 25681529.

 18- Fioravanti M, Buckley AE. Citicoline (Cognizin) in the treatment of cognitive impairment. Clin Interv Aging. 2006;1(3):247-251. doi:10.2147/ciia.2006.1.3.247

 19- Institute of Medicine (US) Committee on Nutrition, Trauma, and the Brain; Erdman J, Oria M, Pillsbury L, editors. Nutrition and Traumatic Brain Injury: Improving Acute and Subacute Health Outcomes in Military Personnel. Washington (DC): National Academies Press (US); 2011. 9, Choline. Available from:

20- Silveri MM et al. Citicoline enhances frontal lobe bioenergetics as measured by phosphorus magnetic resonance spectroscopy. NMR Biomed. 2008;21(10):1066-75

 21- McGlade E. et al., Improved Attentional Performance Following Citicoline Administration in Healthy Adult Women. Food and Nutrition Sciences. 2012;3:769-773.