SANE MD Health & Wellness Guides

Evidence-based articles written by Dr. Matthew Olesiak, MD and the SANE medical team. Browse by health topic or explore our latest research.

Skin Care & Anti-Aging for Adults Over 60

Your skin loses collagen at 1-1.5% per year after age 25, and the decline accelerates after 60. Our guides cover what actually works for mature skin, from daily routines to targeted treatments, all backed by dermatological research.

Skincare Routine for 60-Year-Old Woman (Step-by-Step)

Morning and night routines with product picks for every step.
Best Dark Spot Remover for Mature Skin Over 60

Top products ranked by clinical evidence for age spots.
Best Collagen Supplement for Women Over 60

Types I, II, III compared with dosage and timeline guidance.
Retinol vs Collagen for Wrinkles After 60

Head-to-head comparison. The answer: use both, and here is why.

View all Skin Care articles →

Nerve Health & Neuropathy Support

Over 20 million Americans live with peripheral neuropathy, and the risk rises sharply after age 60. Our guides cover supplements with real clinical evidence, safety warnings your doctor may not mention, and practical relief strategies.

Supplements for Neuropathy in Feet: What Actually Works

7 supplements ranked by evidence tier with dosage ranges.
Best Nerve Support Supplement for Seniors

Alpha-lipoic acid, B12, benfotiamine, and more compared.

View all Nerve Health articles →

Joint & Bone Health for Seniors

Joint pain affects over 50% of adults over 65. From turmeric to collagen, we separate what works from what does not, with evidence tiers so you know exactly how strong the science is.

Best Turmeric Supplement for Joint Pain in Seniors

Curcumin absorption formats compared: Meriva vs BCM-95 vs BioPerine.
Collagen vs Glucosamine for Joint Pain Over 60

68% patient improvement with collagen vs 37% for glucosamine.
Joint Supplements for Seniors That Actually Work

Evidence-ranked by study quality: A, B, and C tier supplements.

View all Supplement articles →

Digestive Health & Gut Support

Your gut microbiome contains 70% of your immune system. Postbiotics, the metabolic byproducts of probiotics, are the latest frontier in digestive science. Our guides explain what works and why.

Benefits of Postbiotic Supplements

How postbiotics differ from probiotics and prebiotics.
Butyrate Supplements: What You Need to Know

The short-chain fatty acid that feeds your colon lining.
20 Ways to Use Postbiotics for a Healthier Gut

Practical strategies for gut health and wellness.

View all Digestive Health articles →

Brain Health & Cognitive Support

Cognitive decline is not inevitable. The right nutrients can support memory, focus, and mental clarity as you age. Our guides cover brain-supportive vitamins, lifestyle strategies, and the science behind them.

Best Eye Vitamins for Seniors: AREDS2 and Beyond

What the research says about macular degeneration prevention.
Best Brain Vitamins for Brain Health

Integrating supplements with lifestyle, diet, and exercise.
The Complete Guide to Vitamins for Brain Health

Which vitamins support memory, focus, and neural function.

View all Brain Health articles →

Shop PRO60+ Supplements

Doctor-formulated supplements designed for adults over 60. Collagen, retinol, nerve support, joint care, and more.

Browse PRO60+ Collection

Nutrition, Diet & Weight Management

The SANE approach is built on 1,300+ studies and endorsed by doctors at Harvard, Johns Hopkins, and the Mayo Clinic. It focuses on food quality over calorie counting, lowering your metabolic setpoint for lasting results.

Fat Burning Breakfast Guide: The SANE Way

Start your day with meals that fuel metabolism, not spike blood sugar.
21 Natural Ways to Balance Hormones for Weight Management

How hormones control your setpoint and what you can do about it.
Natural Blood Sugar Support Supplements

Evidence-based guide to berberine, chromium, and more.
Diabesity: 22 Natural Ways to End This Health Crisis

Where diabetes and obesity overlap, and holistic approaches that help.

View all Nutrition articles →

General Wellness & Vitality

From liver support to dental health, these guides cover the less common but equally important aspects of aging well after 60.

Liver Health Supplements for Adults Over 60

What works for liver support, plus medication interaction warnings.
Vitamins for Teeth & Gum Health After 60

Oral health supplements most people overlook.
Best Supplements for Aging Skin After 60

7 supplements ranked by research evidence for skin health.
Collagen Peptides for Seniors: Complete Guide

Types, dosage by goal, and what to look for when buying.

Real Success Stories

Over 100,000 people have transformed their health with the SANE approach. These are their stories, in their own words.

Christine: From a Broken Neck to Shedding 100 lbs

How Christine overcame a devastating injury and transformed her body.
Jay & Jennifer: From Biggest Losers to SANEst Winners

A couple’s journey to lasting health together.
Judy: Celebrating Retirement and 73 Pounds Gone

Proof that it is never too late to start.

Read more Success Stories →