Weight Loss Supplements that Help Lower Setpoint Weight

An image of a bowl of asparagus salad with strawberries.Have you been eating a SANE diet, performing a higher-quality exercise, getting enough sleep, and practicing stress-reduction techniques daily? Yet, is the decrease in your setpoint weight a little slower than you desire? If so, you might want to consider regularly taking a few key supplements, also known as nutraceuticals.

Weight loss supplements: lower setpoint weight?

Research shows that, when combined with SANE eating and lifestyle upgrades, certain supplements can speed up the setpoint-lowering process. Indeed, these powerful supplements have been proven to increase the fat-burning and setpoint-lowering effects of SANE eating and higher-quality exercise.

Remember, setpoint weight is the weight that your body tries to maintain within a range of 10 to 20 pounds regardless of how little you eat or how much you exercise. Your body takes the number of calories you consume and the number you burn and balances them by adjusting numerous metabolic processes.

So, the only way to enjoy sustainable weight loss is not by calorie and food deprivation but by lowering your setpoint weight. Once you do that, you will lose weight easily and consistently, and once you hit your goal weight, you will not have to worry about regaining it.

And that’s where supplements come in. These supplements, quite simply, can help significantly lower your setpoint weight faster than SANE diet and lifestyle adjustments can do.

And they are much better than diet pills.

Weight loss supplements vs diet pills and setpoint weight

These supplements are also not the same as diet pills. These supplements work with your body’s own system to burn fat and lower setpoint weight. They are natural substances required by the body to lower your setpoint weight. There’s is no question, then, whether these supplements work. The question is, how much do they work? The answer? These supplements are most effective at lowering setpoint weight when combined with SANE eating and lifestyle upgrades.

Diet pills, on the other hand, offer results that are often inconsistent or nonexistent. Like traditional dieting, many brands of diet pills provide only a short-term solution to weight loss at best. For instance, they may promise decreased hunger, increased fat burn, faster metabolism, etc. But if these claims are true — a very big IF — the results are short-lived. As soon as you stop taking those diet pills, your hunger comes back, and so do the pounds. This is because they do nothing to address the underlying cause of weight gain or inability to lose weight: an elevated setpoint.

Plus, many brands of diet pills, even ones claiming to be “all-natural,” can have dangerous and even deadly side effects. Unlike prescription drugs, the FDA does not review dietary supplements for safety and effectiveness before they go to market. The FDA only takes action if certain supplements pose a clear danger to health. This only happens after there have been reports of potentially life-threatening side effects or deaths.

Dangers of diet pills and some “natural” diet supplements

Ephedra, a plant-based appetite suppressant, was all the rage among dieters in the 1990s. (It was the active ingredient in the wildly popular Metabolife diet supplements.) Ephedra is a stimulant known to suppress appetite and speed metabolism leading to weight loss. These diet supplements, however, caused many disturbing side effects. Some of the dangerous and life-threatening side effects of Ephedra include irregular heart rhythm, high blood pressure, chest pain, seizures, and anxiety. Ephedra usage was even linked to some deaths during the 1990s.

This led the FDA to ban the sale of Ephedra and products containing Ephedra in the United States in 2004. This includes products containing the herb ma-huang from which Ephedra is made. (Products containing ma-huang can still be ordered online.)

Prescription diet pills haven’t fared much better. The FDA banned the fenfluramine portion of the popular Fen-Phen (a combination of fenfluramine and phentermine) in 1997 after receiving reports of people suffering from heart valve disease and pulmonary hypertension from its usage. At least one person died. Phentermine is still sold in other weight loss supplements, as its usage was not implicated in those serious side effects.

The FDA also pulled the popular Meridia, a drug said to help speed signals of satiety to the brain to curb overeating, in 2010. Meridia was not only associated with many serious side effects but it was also found to increase the risk of heart attack and stroke in people with a history of cardiac issues.

Learn the exact foods you must eat if you want to finally lose weight permanently. Click here to download your FREE Weight Loss Recipes, the “Eat More, Lose More” Weight Loss Recipes, the “Slim in 6” Cheat Sheet…CLICK HERE TO GET FREE WEIGHT LOSS RECIPES & GUIDES

Supplements for lasting weight loss

Why risk any dangerous or deadly side effects of diet pills when you can take supplements that are truly natural, ones that your body requires to lower your setpoint weight? Why take diet pills that offer only short-term solutions when you can take supplements that help lower the body’s setpoint, leading to permanent weight loss?

Nutraceuticals that help lower setpoint weight

Supplements that help lower setpoint weight are natural chemicals found in foods concentrated down into therapeutic and pharmaceutical grade levels. These nutrients include amino acids, essential fatty acids, vitamins, minerals, and more.

These supplements not only speed the setpoint-lowering effects of SANE dietary and lifestyle upgrades, but they also help improve your overall health. Here are 8 of the most effective supplements for lowering setpoint weight.

1. Inositol

Inositol is a vitamin-like substance found in plants and animals and has been shown to assist in fat transportation and metabolism. Studies also show inositol helps insulin receptors on cells work more efficiently, thereby normalizing insulin levels. Additionally, inositol can help stabilize weight in women suffering from polycystic ovary syndrome (PCOS), which is a condition characterized by insulin resistance, obesity, menstrual disorders, and the elevation of hormones.

The body makes inositol, and it is also naturally present in nuts, fruits, beans, and whole grains. To help lower setpoint weight, take 1,000 milligrams with meals.

2. Choline

Choline is another vitamin-like nutrient that helps with weight loss. It is vital for the proper functioning of every cell in your body. Choline works with inositol to help the body use fat. It also breaks down cholesterol, keeping it from sticking to artery walls.

Egg yolks, beef liver, and cruciferous vegetables contain the highest levels of choline. However, people often do not eat enough choline-containing foods to obtain the optimum amount to lower setpoint weight. To help lower setpoint, take 1,000 milligrams with meals.

3. Biotin

Biotin is a B vitamin that helps regulate insulin and blood sugar. Studies show biotin also assists with the metabolism of fats and proteins. It also supports a healthy digestive system.

Many foods contain small amounts of vitamins. These foods include cauliflower, salmon, nuts, carrots, and chicken. To benefit from its setpoint-lowering ability, take 450 micrograms with meals.

4. Vitamin B-12

Vitamin B-12 is essential for your body to convert nutrients into energy. It also helps prevent neurological inflammation. Many studies show neurological inflammation may be one of the main causes of overweight and obesity. This is because when the hypothalamus in the brain is inflamed, it cannot receive proper messages from the hormones about the amount of body fat you have. It ends up giving you more fat as a precaution against starvation, and this raises your setpoint weight.

Most natural sources of B-12 are animal products, such as meat, dairy, and eggs. Vegetarians and vegans often have trouble obtaining B-12 through their diets, so dietary supplements are a good choice. For help in lowering setpoint, take 100 micrograms with meals.

5. L-Carnitine

L-carnitine, an amino acid, transports fat into the mitochondria, the energy-producing area of the cells. This boosts energy levels and improves the efficiency of fat burning. In fact, several studies show that L-carnitine supplementation increases the rate of fat burning. This helps lower setpoint weight.

Red meat contains the highest levels of L-carnitine. Other foods containing this nutrient include vegetables, legumes, and dairy products. To take advantage of its setpoint-lowering benefits, take 600-1,200 milligrams with meals.

6. Chromium picolinate

Chromium picolinate is an excellent mineral for lowering setpoint weight. Studies show it helps the body process carbohydrates more efficiently while combating insulin resistance. It also helps balance hormone levels and improves blood sugar levels. And that’s not all. Chromium picolinate has also been shown to reduce cravings for sugars and carbs and boost the body’s fat-burning abilities.

Chromium is found in fruits, vegetables, meats, and seafood. However, most sources contain only small amounts of this mineral. To speed up the setpoint-lowering effects of SANE dietary and lifestyle upgrades, take 200 micrograms of chromium picolinate with meals.

7. Coenzyme Q10 (CoQ10)

CoQ10 is a coenzyme that helps generate energy in cells. It is also an antioxidant helping to protect your body from free radicals that damage your cells, causing illness. Studies show CoQ10 also helps convert fats and sugar to energy in cells. It also increases fat burning and helps prevent chronic inflammation. Finally, CoQ10 is known to protect and even strengthen the heart.

The body makes CoQ10; however, levels of this nutrient naturally decline with age. CoQ10 is naturally found in high levels in beef, fish, and organ meats. To take advantage of its setpoint-lowering abilities, take 10 milligrams with meals.

8. Vitamin D3

Vitamin D is mostly known for its ability to build strong bones and teeth. But this nutrient does much more than that. Research indicates vitamin D protects against many health conditions, including heart disease, type 2 diabetes, and metabolic syndrome. Having an adequate level of vitamin D3 can prevent systemic and brain inflammation and reduce insulin resistance, thus lowering setpoint weight.

There are two types of vitamin D supplements: D2, derived from plant sources, and D3, derived primarily from animal sources. Vitamin D3 is created when your skin is exposed to sunlight, which is why it is sometimes called the “sunshine vitamin,” and research suggests it is more effective at raising blood levels of vitamin D than D2. Though many foods are fortified with vitamin D, only a few foods naturally contain this nutrient. Some of these foods include eggs, sardines, and sockeye salmon.

Research suggests that many people are deficient in vitamin D. To use this powerful nutrient to lower setpoint weight, take 5,000 IU of D3 with meals.

Lower Your setpoint weight with supplements and the SANE diet

An image of several classes of raspberry juice, with whole raspberries and blueberries on the table.As previously mentioned, these supplements will not work to lower setpoint weight if not used in combination with SANE dietary and lifestyle upgrades. Here is some information on SANE eating to give you the best chance of permanently shedding those extra pounds.

The SANE diet emphasizes eating more rather than fewer foods. The idea is to become so full of SANE foods you’ll have no room for inSANE ones. So…instead of counting calories, depriving yourself, and thinking about all the foods you can’t have…start thinking about foods you can eat — and plenty of them.

Think savory steak, mouth-watering salmon, rich dark chocolate, sweet-tasting coconut, and a variety of setpoint-lowering non-starchy veggies. Yum. SANE foods fill you up fast and keep you full longer. They eliminate your cravings for sugars and starch. You’ll be pleasantly full. Yet, you’ll unconsciously consume fewer calories, which creates a calorie deficit. But because you’re not hungry or deprived and your cells are fully nourished, your body will start burning fat and lowering your setpoint weight.

The foods on the SANE diet are so easy to remember, too. Simply choose foods from the following 4 food groups:

Non-starchy vegetables

10+ servings per day. Either fill half your plate with non-starchy veggies at each main meal or blend 3-4 servings into a setpoint-lowering green smoothie. Examples include:

  • Broccoli
  • Cauliflower
  • Cucumber
  • Eggplant
  • Endive
  • Kale
  • Spinach
  • Swiss Chard

Nutrient-dense proteins

3-5 servings per day. 30-55 grams per main meal. Fill one-third of your plate with nutrient-dense proteins. Examples include:

  • Chicken
  • Cottage Cheese
  • Egg Whites
  • Grass-Fed Beef
  • Liver
  • Nonfat Greek Yogurt
  • Salmon
  • Tuna

Whole-food fats

3-6 servings per day. Fill the remaining one-third of your plate with whole-food fats. Examples include:

  • Almonds
  • Avocado
  • Chia Seeds
  • Cocoa/Cacao
  • Coconut
  • Flax Seeds
  • Macadamias
  • Olives

Low-fructose fruits

0-3 servings per day. Examples include:

  • Blueberries
  • Cherries
  • Goji Berries
  • Grapefruit
  • Lemons
  • Oranges
  • Peaches
  • Strawberries

Try to eat foods from the first three food groups at every main meal because they work together to naturally curb hunger, trigger fat-burning hormones, and lower setpoint weight.

Don’t Forget SANE Lifestyle Upgrades to Lower Setpoint Weight

There are a couple of SANE lifestyle upgrades that, along with the SANE diet and taking certain supplements, helps lower your setpoint weight more quickly. They are smarter by exercising, de-stressing, and getting more sleep.

Smarter (eccentric) exercise

Eccentric exercise emphasizes the lowering portion of the exercise. So, if you’re performing a dumbbell curl with your arms, the eccentric portion of the movement is when you’re lowering the weight back down and away from your chest. Eccentric exercise has been proven to clear hormonal clogs, speed metabolism, and lower setpoint weight. You can make any exercise an eccentric one by slowly performing the eccentric portion of the movement to a count of 10 and then repeat a few times. Because eccentric exercise uses all muscle fibers, you can perform them only once a week per body part.


Studies show chronic stress promotes weight gain. To prevent this, try to de-stress every day. This can be as simple as just performing a few deep breathing exercises several times a day or as complicated as practicing Tai Chi. Anything you enjoy doing will de-stress you, so look for things that make you happy — and do them. This includes, by the way, making love the ultimate stress reducer!

Getting more sleep

Studies also show lack of sleep causes weight gain. This is because, among other things, sleep deprivation dysregulates hormones causing hunger and cravings for carbs and sweets. To help lower setpoint weight, try to get at least 7-8 hours of uninterrupted sleep each night.

Next step: Learn which supplements can help lower setpoint weight with SANE

Ready to finally break free from the yo-yo dieting rollercoaster by balancing your hormones and lowering your body’s setpoint weight?

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